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Updated: Jun 18, 2025

Generation of Native, Untagged Huntingtin Exon1 Monomer and Fibrils Using a SUMO Fusion Strategy
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Generation of Native, Untagged Huntingtin Exon1 Monomer and Fibrils Using a SUMO Fusion Strategy

Published on: June 27, 2018

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解开N端亨廷寡合体的分子复杂性:对多态结构的洞察

Neha Nanajkar1, Abhilash Sahoo2,3, Silvina Matysiak4

  • 1Department of Biology, University of Maryland, College Park, Maryland 20740, United States.

The journal of physical chemistry. B
|August 2, 2024
PubMed
概括

亨廷顿病与亨廷丁蛋白聚合有关. 这项研究揭示了多重氨酸的长度如何影响蛋白质结构和毒性,为神经退行性疾病提供了新的治疗点.

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