在有显著三腹吐的患者中,右心房功能的预后值
Takahiro Nishihara1, Yoichi Takaya1, Rie Nakayama1
1Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
ESC heart failure
|August 2, 2024
概括
通过RA全球纵向应变 (RAGLS) 测量右心房 (RA) 功能,与显著三回 (TR) 患者的不良结果有关. 较低的RAGLS预测死亡率和心力衰竭住院,有助于风险分层.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏成像 - - 心脏成像
背景情况:
- 右心室 (RV) 功能障碍是三回 (TR) 患者不良结果的已知预测因素.
- 在这种患者群体中,右心房 (RA) 功能的预后价值在很大程度上仍未被探索.
- 了解RA的功能可能为显著的TR提供了对风险分层的新见解.
研究的目的:
- 为了研究右心房 (RA) 功能与中度至严重三腹 (TR) 患者的临床结果之间的关联.
- 为了确定RA全球纵向菌株 (RAGLS) 是否可以作为这一队列中不良事件的预测因素.
- 探索RA功能在显著TR患者风险分层中的作用.
主要方法:
- 对169名门诊患者的回顾性分析,由于心脏左侧疾病而导致中度或重度TR.
- 排除心房的患者,以确保准确的2D斑点跟踪心声回声分析.
- 测量RA全球纵向应变 (RAGLS) 和RA体积指数 (RAVI) 使用2D斑点跟踪回声心脏学.
- 事件的定义是所有原因的死亡率或由于心力衰竭而入院的事件,在平均13个月的随访期间.
主要成果:
- 在随访期间,共发生了19起事件 (14例死亡,5例心力衰竭住院).
- 与没有事件的患者相比,具有不良事件的患者表现出明显较低的RAGLS (13%±10%对18%±9%,P=0.02).
- 在多变量分析中,低RAGLS (≤16.2%) 和高RAVI (≥50mL/m2) 独立地与4.5倍的不良事件风险增加有关,即使考虑到VR功能障碍.
结论:
- 右心房全球纵向应变 (RAGLS) 是所有原因死亡率和心力衰竭住院治疗的重要独立预测因子,患者有显著的三回 (TR).
- 通过RAGLS评估的RA功能,为具有显著TR的患者的风险分层提供了有价值的预后信息.
- 这些发现强调了在对TR患者的综合评估中评估RA功能的重要性.
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