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Updated: Jun 18, 2025

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
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在重症新生儿中使用万科米辛的生理学基础的药理动力学建模:评估病理生理变化的影响

Weiwei Shuai1, Jing Cao1, Miao Qian2

  • 1Department of Pharmacy, Women's Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital, Nanjing, Jiangsu, P. R. China.

Journal of clinical pharmacology
|August 2, 2024
PubMed
概括

开发了一种基于生理学的药理动力学 (PBPK) 模型,改善了危急病患新生儿的万科米辛剂量. 这种增强的模型解释了病理生理学变化,从而导致更精确的剂量建议.

关键词:
在PK-Sim中.这是新生儿新生儿.病理生理学 病理生理学基于生理学的药物动力学.这就是Vancomycin.

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