男性体重指数对精液分析参数和体外受精结果的影响
Ana Z Nikolic1, Svetlana Dragojevic-Dikic1,2, Jovana Kocic1
1Clinic for Gynecology and Obstetrics Narodni Front, Belgrade, Serbia.
Medicine
|August 2, 2024
概括
在接受体外受精 (IVF) 的男性中,更高的体重指数 (BMI) 不会显著影响精液分析. 然而,超重和肥胖男性的优质胚胎较少,影响了试管婴儿成功率.
科学领域:
- 生殖医学 生殖医学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 全球肥胖和男性不孕率的增加表明,超重和男性生育能力下降之间存在联系.
- 之前的研究表明,身体质量指数 (BMI) 对精液质量和生育结果的影响有不同的结果.
研究的目的:
- 调查男性体重指数 (BMI) 对精液参数和不孕夫妇体外受精 (IVF) 结果的影响.
主要方法:
- 一项队列研究包括411名接受试管婴儿的男性,但不包括患有亚精子症或特定疾病的男性.
- 男人根据BMI进行分类:体重不足,体重正常,超重和肥胖.
- 评估的精液参数包括体积,pH,数量,运动性和形态;试管婴儿结果评估了胚胎数量,质量和怀孕率.
主要成果:
- 在BMI组间的精液分析参数中没有发现显著差异.
- 在BMI和精液参数之间存在微弱,微不足道的相关性.
- 与正常体重和体重不足男性相比,超重和肥胖男性的优质胚胎数量和比例明显较低 (P=0.041).
结论:
- 男性的BMI不会显著影响受试管婴儿治疗的不孕男性的精液分析参数.
- 较高的BMI与优质胚胎数量和比例的减少有关,这可能会影响体外受精成功.
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