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Updated: Jun 18, 2025

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来自Daphne genkwa (Thymelaeaceae) 的花中的生物活性达芬二烯

Qingsong Zhu1, Hongbin Duan1, Lijun Yang1

  • 1Xinyang Agricultural and Forestry University, Xinyang, China.

Natural product research
|August 2, 2024
PubMed
概括

从Daphne genkwa的花中分离出了两种新的达芬二烯,即Genkwadanes J和K. 这些化合物,以及已知的类似物,对K562和MCF-7癌细胞系表现出显著的细胞毒性.

关键词:
达妮·詹克瓦 (Daphne Genkwa) 是一个著名的作家.细胞毒性活动的细胞毒性.达芬二甲烯 (DAPHNAE) 是一种二甲烯.这种植物是thymelaeaceae.

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In a Diels–Alder reaction, the diene is usually an electron-rich system and acts as a nucleophile, whereas the dienophile is electron-deficient and functions as an electrophile. Much like the diene, the nature of the dienophile significantly impacts the outcome of the reaction. 
Characteristics of Dienophiles
Generally, the best dienophiles are alkenes containing electron-withdrawing substituents such as carbonyl, nitrile, and nitro groups. The feasibility of a Diels–Alder reaction depends...
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