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在SLE患者中,CD39+CD73+B细胞子集的减少频率与疾病活性相关

Kunzhan Dong1, Ying Wang2, Yao Yao3

  • 1Department of Clinical Laboratory Medicine, Nanjing Drum Tower Hospital, Clinical College, Jiangsu University, Nanjing, Jiangsu 210008, China.

International immunopharmacology
|August 2, 2024
PubMed
概括

系统性红斑狼 (SLE) 患者的CD39+CD73+B细胞和腺水平降低,与疾病活性相关. 这一途径为SLE提供了潜在的新免疫治疗点.

关键词:
亚丁氨酸 (Adenosine) 是一种氨基酸.B 细胞细胞B 细胞细胞CD39 CD39 是一个CD73 CD73 CD73 CD73 CD73 CD73 CD73 CD73 CD73 CD73 CD73一个小小的东西.斯莱达伊 (SLEDAI) 是一个叫做"斯莱达伊"的公司.

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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