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你什么时候恢复? 使用急性呼吸道感染问卷确定切断点
Eskild Johansen1, Volkert Siersma2, Malene P Hansen1
1The Research Unit for General Practice, Department of Clinical Medicine, Aalborg University, Denmark.
概括
研究人员使用ARTI问卷确定了特定的切断点,以定义急性呼吸道感染 (ARTIs) 的恢复. 这有助于标准化研究和临床实践,以便更好地诊断和比较ARTI治疗.
科学领域:
- 临床医学 临床医学
- 呼吸系统医学 呼吸系统医学
- 患者报告的结果
背景情况:
- 急性呼吸道感染 (ARTIs) 在一般实践中存在诊断和康复评估的挑战.
- 缺乏精确的恢复定义阻碍了ARTI研究,包括治疗比较和诊断优化.
研究的目的:
- 通过验证的ARTI问卷 (ARTIQ) 来确定确定ARTI回收的截止点.
- 提供患者报告的结果测量作为ARTI临床研究中恢复的代理.
主要方法:
- 259名参与者被分为ARTI和非ARTI队列.
- 用历史图和AUC分析了ARTIQ尺寸的歧视性效应.
- 接收器运行特征曲线确定了ARTI症状存在/不存在的切断点.
主要成果:
- "物理上空气道"和"物理下空气道"的维度显示出最高的分辨力.
- 将这些维度结合起来,得出AUC为0.97.
- 对于选定的切断点,确定了灵敏度,特异性和预测值.
结论:
- 确定的患者报告的结果截止点作为ARTI恢复的代理.
- 选择特定的切断点应根据研究项目的临床背景进行调整.
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