益生菌对睡眠参数的影响:系统审查和元分析
Hiroshi Ito1, Yuna Tomura2, Yuki Kitagawa1
1Division of General Internal Medicine, Department of Internal Medicine, Tokyo Medical University Ibaraki Medical Center, Inashiki, Ibaraki, Japan.
Clinical nutrition ESPEN
|August 2, 2024
概括
益生菌可以改善睡眠质量,这是匹兹堡睡眠质量指数 (PSQI) 和Oguri-Shirakawa-Azumi (OSA) 睡眠库存得分的降低表明的. 需要进一步的研究来探索具体的睡眠参数效应.
科学领域:
- 微生物学 微生物学
- 睡眠医学 睡眠医学
- 营养科学 营养科学
背景情况:
- 睡眠障碍是一个日益严重的公共卫生问题,影响着整体幸福感.
- 益生菌,即带有健康益处的活微生物,正在研究它们在睡眠调节中的潜在作用.
研究的目的:
- 对益生菌对睡眠参数的影响进行系统的文献审查和元分析.
- 提供关于益生菌补充和睡眠结果的当前证据的全面概述.
主要方法:
- 在PubMed,Cochrane图书馆和Ichushi数据库中对安慰剂受控随机对照试验进行系统的文献搜索.
- 数据提取和对包含的研究进行偏差风险评估.
- 进行元分析,以统计评估益生菌对睡眠变量的影响.
主要成果:
- 分析包括了15项随机对照试验.
- 益生菌补充剂在4至16周内显著降低了匹兹堡睡眠质量指数 (PSQI) 的得分,表明睡眠质量有所改善.
- 益生菌还改善了Oguri-Shirakawa-Azumi (OSA) 睡眠库存中的第1因子 (起床时的嗜睡) 和第4因子 (清爽) 评分.
结论:
- 益生菌显示出改善睡眠质量的潜力,基于PSQI和OSA库存措施.
- 需要进一步的研究来阐明对特定睡眠参数的影响,并解决研究的局限性,包括发现的偏差风险.
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