人类肠道微生物群的组成与国际旅行有关
D Henares1, V Monsalvez2, Pedro Brotons3
1Department of RDI Microbiology, Institut de Recerca Sant Joan de Déu, Hospital Sant Joan de Déu, 08950, Esplugues de Llobregat, Barcelona, Spain; CIBER Center for Epidemiology (CIBER) and Public Health, Carlos III Health Institute (CIBERESP, ISCIII), Avenida Monforte de Lemos, 3-5, 28029, Madrid, Spain.
Travel medicine and infectious disease
|August 2, 2024
概括
国际旅行显著改变了肠道微生物群的组成和多样性. 与非旅行者相比,旅行者表现出更多的细菌多样性和独特的微生物特征,影响健康考虑.
科学领域:
- 微生物学 微生物学
- 人类健康 人类健康 人类健康
- 旅行 医学 旅行 医学
背景情况:
- 国际旅行使个人接触到新的环境,可能会影响肠道微生物群.
- 了解因旅行而导致的肠道微生物群组成和多样性的变化,对于评估健康风险至关重要.
研究的目的:
- 调查非欧洲国家长期逗留对肠道微生物群的影响.
- 分析微生物群组成,多样性和与旅行,饮食和社交联系相关的动态的变化.
主要方法:
- 对两个潜在队列的分析:一个纵向旅行队列和一个横截面队列,将旅行者/移民与对照进行比较.
- 便样本采集用于16S rRNA基因测序以表征肠道微生物群.
- 从参与者那里收集人口统计和流行病学数据.
主要成果:
- 旅行与更高细菌多样性的趋势有关 (香农指数,植物遗传多样性).
- 特定的细菌属,如Escherichia/Shigella,Bacteroides和Parabacteroides在旅行者中得到了丰富.
- 确定了三个不同的肠道微生物群,其中两个主要在旅行者中发现,显示出差异性的丰富性和多样性.
结论:
- 国际旅行显著影响肠道微生物群的组成和多样性.
- 微生物群的弹性和多样性是理解旅行相关健康影响的重要因素.
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