眼的时间 通过光学连贯性断层扫描和视野在眼中的进展检测 非洲血统的个人
Jo-Hsuan Wu1, Sasan Moghimi1, Evan Walker1
1From the Hamilton Glaucoma Center (J-H.W., S.M., E.W., T.N., L.M.Z., R.N.W.), Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California, San Diego, La Jolla, California, USA.
American journal of ophthalmology
|August 2, 2024
概括
在非洲裔个体中,视网膜神经纤维层厚度 (RNFLT) 的进展检测得比视野 (VF) 平均偏差 (MD) 快. 这突出了RNFLT的重要性.
科学领域:
- 眼科医生 眼科 眼科
- 神经科学是一个神经科学.
- 医疗成像医学成像
背景情况:
- 玻璃眼是全球不可逆转失明的主要原因.
- 非洲血统的个人患青光眼的患病率和风险更高.
- 早期发现青光眼的进展对于及时干预和维护视力至关重要.
研究的目的:
- 用视网膜神经纤维层厚度 (RNFLT) 与视野 (VF) 平均偏差 (MD) 在非洲血统 (AD) 个体中比较检测青光斑进展的时间.
主要方法:
- 一个回顾性队列研究,涉及AD个体的眼睛与绿眼病.
- 利用了两项多中心研究的数据,其中包括至少两年/五次RNFLT检查和24-2 VF检查.
- 使用线性混合效应模型和模拟纵向数据分析了RNFLT和VF MD恶化的速度.
主要成果:
- 包括来自128名阿尔茨海默病患者的184只眼睛.
- 视网膜神经纤维层厚度 (RNFLT) 与视野 (VF) 平均偏差 (MD) 相比,发现进展的平均时间较短.
- 在RNFLT检测的眼睛中,轻度 (≥1年早) 和中度至高级玻璃眼病 (∼0.5年早) 的进展都更快.
结论:
- 计算机模拟表明,RNFLT的进展在非洲裔个体中比VF MD的进展更早被检测出来.
- 这些发现强调了将RNFLT测量纳入监测该群体中渐进性绿眼病的重要性.
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