胆结石:预防,诊断和治疗
Frank Lammert1, Henning Wittenburg2
1Health Sciences, Hannover Medical School (MHH), Hannover, Germany.
Seminars in liver disease
|August 2, 2024
概括
胆结石影响了许多成年人,治疗方法从药物到手术. 未来的研究旨在开发预防胆结石的新策略.
科学领域:
- 胃肠病学 胃肠病学
- 肝病学 肝病学是一种肝病学.
- 外科胃肠道外科手术
背景情况:
- 胆结石 (胆结石) 很常见,影响到20%的成年人.
- 超过20%的胆结石患者可能会出现症状或并发症.
- 风险因素包括通过饮食或减肥手术显著减肥.
研究的目的:
- 总结目前对胆结石及其并发症的治疗策略.
- 强调需要采取新的预防措施,防止胆结石形成.
主要方法:
- 对胆结石的当前医疗和手术干预措施的审查.
- 讨论药理疗法,如乌尔索氧胆酸等药理疗法.
- 强调对症状性胆结石和并发症的内镜和手术程序.
主要成果:
- 乌尔索多西胆酸可以降低减肥后胆结石形成风险.
- 腹腔镜胆囊切除术是症状胆结石的标准.
- 胆汁结肠用NSAID,抗药或阿片类药物进行管理.
- 急性胆囊炎需要早期胆囊切除术.
- 具有症状的胆道结石经过内镜治疗.
- 急性胆道炎需要迅速的抗感染疗法.
结论:
- 目前的胆结石治疗在很大程度上是侵入性的,依赖于内镜和手术.
- 增加对胆结石遗传学和病理生理学的理解.
- 迫切需要创新的,不那么侵入性的胆结石预防策略.
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