药剂师对活体捐献者脏移植候选人的药剂坚持性评估的程序评估
Linh Nguyen1, Abigail Forte1,2, Gregory Malat1,2
1Department of Pharmacy Services, Hospital of University of Pennsylvania, Philadelphia, PA, USA.
Progress in transplantation (Aliso Viejo, Calif.)
|August 2, 2024
概括
许多脏移植候选人报告药物不坚持问题,即使在使用坚持策略时也是如此. 标准化的评估可以识别这些问题,以实现个性化的教育和改善移植结果.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 移植 移植 移植 移植
- 药理学 药理学是指药理学的学科.
背景情况:
- 药物坚持对于移植成功至关重要.
- 标准化评估有助于评估移植候选人的坚持.
- 活体捐赠者的移植需要经过精心的手术前评估.
研究的目的:
- 用标准化评估来评估活体捐赠者移植候选人的药物坚持.
- 识别与药物不服药相关的特征.
- 描述这些候选人使用的坚持策略.
主要方法:
- 对181名成年HIV阴性活体捐赠者移植候选人的回顾性分析.
- 手术前由药剂师评估的药物坚持.
- 被遗漏/延迟或在没有建议的情况下停止服用药物所定义的坚持问题.
- 坚持策略包括药盒,提醒和补充跟踪.
主要成果:
- 45%的候选人表示,他们对合规问题感到担忧.
- 93%的人表示使用了坚持的策略.
- 基于年龄,性别,种族,先前的移植/透析或教育水平的依从性问题没有显著差异.
- 高等教育与更多地使用守策略相关 (96%对86%).
结论:
- 很大一部分移植候选人表现出药物不服药的担忧,尽管使用了坚持的策略.
- 药物坚持性评估对于识别不坚持性风险至关重要.
- 个性化药物教育可以根据评估结果量身定制.
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