在患有丸癌的男性中进行逆侧丸活检
John Pfail1, Ines Santiago2, Thomas L Jang1
1Section of Urologic Oncology, Rutgers Cancer Institute and Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
European urology focus
|August 2, 2024
概括
对丸生殖细胞瘤 (TGCTs) 的常规 contralateral 丸活检进行辩论. 本综述考察了关于检测其他丸中的生殖细胞瘤 in situ (GCNIS) 的活检的指导方针和问题.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 丸生殖细胞瘤 (TGCTs) 很罕见,在欧洲和北美每10万名男性中发生7-10例.
- 一小部分 (2-5%) 的单侧TGCT患者在对侧丸中存在生殖细胞瘤 (GCNIS),癌症进展风险高于50%.
研究的目的:
- 审查当前关于TGCT患者逆侧丸活检的指导方针建议.
- 评估常规活检对GCNIS检测的争议和影响.
主要方法:
- 对当前指导方针建议的文献综述.
- 在TGCT管理中分析与对侧丸活检有关的问题.
主要成果:
- 在TGCT患者中常规使用逆侧丸活检仍然存在争议.
- 查和治疗GCNIS只有当患者的结果改善,对丸功能影响最小时才合理.
结论:
- 对逆侧丸活检的决定需要仔细考虑风险,益处和对丸功能的影响.
- 需要进一步评估TGCT患者GCNIS的风险因素和治疗选择.
相关概念视频
Disorders of the Male Reproductive System
373
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
373
Testes: Histology
791
A tough, fibrous membrane, the tunica albuginea, covers the testes, extending inward to form fibrous partitions or septa, dividing them into internal compartments called lobules. Each lobule has 1 to 3 tightly coiled seminiferous tubules where sperm production occurs. These tubules merge into a tubular network at the back of the testis, known as the rete testis. It connects to 15 to 20 efferent ductules, leading to the epididymis.
The spermatogenic cells, responsible for producing sperm, are...
The spermatogenic cells, responsible for producing sperm, are...
791
Testes: Gross Anatomy
1.8K
The testes, also known as testicles, are the male gonads. They are housed within the scrotum, a sac-like structure located beneath the penis. The scrotum's primary role is to regulate the temperature of the testes, which is crucial for sperm production.
Each testis is surrounded by the tunica albuginea, a dense connective tissue layer that provides structural support and protection. This layer is covered by an outer serous membrane called the tunica vaginalis, which helps reduce friction...
Each testis is surrounded by the tunica albuginea, a dense connective tissue layer that provides structural support and protection. This layer is covered by an outer serous membrane called the tunica vaginalis, which helps reduce friction...
1.8K


