青少年焦虑和抑郁症数据集的人类连接组项目
N A Hubbard1,2, C C C Bauer3,4, V Siless5,6
1Department of Psychology, University of Nebraska-Lincoln, Lincoln, NE, USA. nhubbard5@unl.edu.
Scientific data
|August 2, 2024
概括
波士顿青少年抑郁和焦虑神经成像 (BANDA) 研究提供了丰富的神经成像和临床数据从青少年,包括那些焦虑和抑郁障碍. 这个资源支持青少年心理健康的研究.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 发展心理学 发展心理学
背景情况:
- 青少年心理健康障碍,包括焦虑和抑郁症,是严重的公共卫生问题.
- 在青春期了解这些疾病的神经生物学基础对于开发有效的干预措施至关重要.
- 现有的研究对这一群体的综合,纵向神经成像数据有局限性.
研究的目的:
- 描述来自波士顿青少年抑郁和焦虑神经成像 (BANDA) 研究的主要数据和资源.
- 为了使这个新型数据集,人类结合体项目 (HCP) 的一个分支,公开可用于研究.
- 促进青少年精神病理学及其神经相关的研究.
主要方法:
- 收集了215名青少年 (年龄在14-17岁) 的截面和纵向数据,其中152人被诊断为焦虑和/或抑郁障碍.
- 获得的结构性 (T1/T2加权),功能性 (静止状态和基于任务的) 和扩散加权的MRI扫描.
- 收集了临床采访,认知,神经心理,自我报告和纵向临床数据.
主要成果:
- 班达研究提供了一个全面的数据集,包括未经处理和最低限度预处理的神经成像数据.
- 包括详细的临床评估,认知测量和心理病理方面的自我报告数据.
- 在6个月和12个月的纵向数据可用,提供了对发育轨迹的洞察力.
结论:
- 班达数据集是研究青少年大脑发育和心理健康的有价值的,公开可访问的资源.
- 研究人员可以利用这些数据来研究青少年焦虑和抑郁的神经基础.
- 数据的综合性支持发育神经科学和精神病学的各种研究问题.
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