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Updated: Jun 18, 2025

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Published on: June 27, 2020

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类域介导的ARID1A的相分离促进了尤文肉瘤的致癌潜力

Yong Ryoul Kim1, Jaegeon Joo2, Hee Jung Lee3

  • 1Creative Research Initiatives Center for Epigenetic Code and Diseases, School of Biological Sciences, Seoul National University, Seoul, South Korea.

Nature communications
|August 2, 2024
PubMed
概括

富含AT的交互域含有蛋白1A (ARID1A) 通过相分离形成液体凝结物,促进尤宁肉瘤的进展. 破坏这个过程会减少癌细胞的生长和入侵,这表明了治疗点.

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