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对患有功能衰竭的儿童和年轻人所经历的症状进行系统审查
Zoe Jacob1, Lucy Plumb2,3, Louise Oni4,5
1Dept. of Medical Paediatrics, Royal Aberdeen Children's Hospital, NHS Grampian, Aberdeen, UK. zoe.jacob@nhs.scot.
Pediatric nephrology (Berlin, Germany)
|August 2, 2024
概括
患有功能衰竭的儿童和年轻人经历了高症状负担,特别是睡眠和心理健康问题. 需要更多的研究来了解和有效地管理这些症状在终身护理.
科学领域:
- 儿科脏病学 儿科脏病学
- 抚慰性护理是一种缓解性护理.
- 生活质量研究 研究 生命质量研究
背景情况:
- 功能衰竭显著影响儿童和青少年 (CYP) 的生活质量 (QoL).
- 功能衰竭的CYP所经历的症状负担,特别是临终期的症状负担,没有得到充分的证据.
- 虽然脏移植是首选,但对许多功能衰竭的CYP来说,支持性终身护理至关重要.
研究的目的:
- 系统地审查有关衰竭临终期CYP患者症状负担的文献.
- 识别和分类这个人群所经历的普遍症状.
- 突出目前关于症状管理的研究中的差距.
主要方法:
- 在三个数据库中进行了系统的文献审查.
- 确定并选了涉及21岁以下患有功能衰竭的CYP研究.
- 提取了有关症状的数据,并使用BMJ AXIS工具评估了研究质量.
主要成果:
- 该审查分析了35项研究,包括2862个患有慢性脏病 (CKD) 的CYP,57%患有5期CKD.
- 常见的症状包括不安腿综合征,睡眠障碍,抑郁,焦虑,胃肠道问题,,和头痛.
- 在症状定义和评估方法中发现了显著的异质性,疼痛和便秘的表现不佳.
结论:
- 关于CKD的CYP中症状负担的证据严重缺乏.
- 观察到睡眠,心理健康,头痛,皮肤和胃肠道症状的高患病率.
- 迫切需要共识性建议来评估和管理CYP患者的症状,其中CKD临终期患者的症状.
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