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Updated: Jun 18, 2025

The Use of Mouse Splenocytes to Assess Pathogen-associated Molecular Pattern Influence on Clock Gene Expression
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Published on: July 24, 2018

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开发一种表观遗传时钟,抵抗免疫细胞组成的变化

Alan Tomusiak1,2, Ariel Floro1,2, Ritesh Tiwari1

  • 1Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, 94945, CA, USA.

Communications biology
|August 2, 2024
PubMed
概括

由于免疫细胞组成的变化,表观遗传钟可能不准确地预测年龄. 一个新的时钟,IntrinClock,从细胞类型中分离了内在衰老,揭示了真正的与年龄相关的变化和逆转年龄的潜力.

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