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Updated: Jun 18, 2025

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对于在MOR重审的稳健β-arrestin2结合的关键酸化位点

Owen Underwood1,2, Sebastian Fritzwanker3, Jaqueline Glenn1,2

  • 1Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, Queen's Medical Centre, University of Nottingham, Nottingham, UK.

Communications biology
|August 2, 2024
PubMed
概括

G蛋白结合受体激酶 (GRK) 亚家族不同调节片受体 (MOR) 酸化. GRK2/3,但不是GRK5/6,促进关键的MOR位点的酸化,影响beta-arrestin招募和阿片类药物耐受性.

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