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Updated: May 8, 2026

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在实验性自身免疫性肝炎中,FGF4通过减少M1巨分化来改善肝炎炎症

Jing Lin1,2, Hong-Wei Lin3, Yu-Xing Wang3

  • 1Zhejiang Provincial Key Laboratory for Accurate Diagnosis and Treatment of Chronic Liver Diseases, The First Affiliated Hospital of Wenzhou Medical University, Hepatology Institute of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China. linjing137999@163.com.

Journal of translational medicine
|August 2, 2024
PubMed
概括

纤维细胞生长因子4 (FGF4) 调节M1巨细胞极化,为自身免疫性肝炎 (AIH) 提供了潜在的新疗法. 通过调节巨细胞表型,FGF4的使用可降低肝炎.

关键词:
实验性的自身免疫性肝炎纤维细胞生长因子4M1巨细胞两极分化在PI3K/AKT信号通路中.

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