评估益生菌对菌细菌的有效性:随机对照临床研究
Didem Sakaryalı Uyar1,2, Aylin Üsküdar Güçlü3, Ekin Çelik4
1Department of Pediatric Dentistry, Faculty of Dentistry, Başkent University, Ankara, Türkiye. dsakaryali@baskent.edu.tr.
BMC oral health
|August 2, 2024
概括
在牙损伤治疗后使用益生菌显著降低了儿童的Streptococcus mutans水平. 然而,在这项为期六个月的研究中,益生菌没有影响乳酸菌种类的数量.
科学领域:
- 口腔健康研究研究 口腔健康研究
- 微生物学 微生物学
- 儿科牙科 儿科牙科
背景情况:
- 益生菌,有益的活体细菌,正在研究它们对口腔健康的影响.
- 在全面治疗牙损伤后,益生菌在控制口腔细菌方面的有效性仍然是研究领域.
研究的目的:
- 评估益生菌补充剂对Streptococcus mutans和Lactobacillus物种水平的影响.
- 在全身麻醉下接受牙损伤治疗的儿科患者的细菌计数进行比较,使用或不使用益生菌.
主要方法:
- 一项涉及58名儿童患者的研究,这些患者在全身麻醉下接受牙损伤治疗.
- 患者被分为两组:一组接受治疗后益生菌 (A组) 和对照组 (B组).
- 在治疗前 (T0) 和治疗后一,三,六个月 (T1,T2,T3) 收集唾液样本,用于实时PCR细菌计数分析.
主要成果:
- 在所有随访点 (p <0.05) 中,与对照组相比,在益生菌组中观察到Streptococcus mutans水平的统计显著降低.
- 在益生菌和对照组 (p ≥0.05) 之间,在乳杆菌物种数量上没有发现统计学上显著的差异.
结论:
- 益生菌补充剂,结合全面的牙损伤治疗,有效地降低了Streptococcus mutans水平.
- 益生菌的使用并没有显示出对研究小儿群体中Lactobacillus物种水平的显著影响.
相关概念视频
01:28Antimicrobial Effectiveness
2.3K
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
2.3K
01:22Probiotics
299
Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
299