患有偶发心脏吸收的患者在骨光学上患病率和特征
Jihee Son1,2, Yeon-Hee Han2,3, Sun Hwa Lee4,5
1Division of Cardiology, Department of Internal Medicine, Jeonbuk National University Medical School, Jeonju, Republic of Korea.
Journal of cardiovascular imaging
|August 2, 2024
概括
偶发的横静氨酸心肌粉症 (ATTR-CA) 在骨扫描中很少见,但在心脏吸收和没有末期病的老年患者中需要进一步调查. 早期诊断可以带来及时治疗,如tafamidis等药物.
科学领域:
- 核医学是一种核医学.
- 心脏病学 心脏病学
- 罕见疾病是一种罕见的疾病.
背景情况:
- 骨光学越来越多地用于诊断心脏粉症 (ATTR-CA).
- 这项研究评估了偶然心脏吸收的发生率和特征,以及因其他原因在骨光学扫描期间发现的ATTR-CA.
研究的目的:
- 为了确定在骨光学上偶发心脏吸收的频率.
- 为了确定与偶然的ATTR-CA.相关的临床特征.
- 为了评估骨光学对意想不到的ATTR-CA的诊断产量.
主要方法:
- 对61,432项骨光学研究 (2011-2022) 的回顾性审查.
- 排除了接受已知ATTR-CA.scintigraphy的患者.
- 包括2级或3级心脏吸收患者,分为可能的ATTR-CA和非CA组.
主要成果:
- 在32,245名患者中,有23名患者 (0.07%) 呈现2级或3级心脏吸收.
- 14名患者 (60.9%) 被归类为可能的ATTR-CA; 5人最终被诊断为ATTR-CA.
- 与非CA患者相比,ATTR-CA患者年龄较大,患末期病的可能性较小.
结论:
- 偶然的ATTR-CA是不常见的,但重要的.
- 在老年患者中考虑ATTR-CA,心脏吸收无法解释,特别是没有末期脏疾病的老年患者.
- 在这种情况下,建议对ATTR-CA进行进一步的工作,以控制心力衰竭.
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