哥斯达黎加的黄金面裂,1996-2021年:对监测数据的分析
María de la Paz Barboza-Argüello1, Adriana Benavides-Lara1
1Costa Rican Birth Defects Register Center (CREC), Costa Rican Institute of Research and Education in Nutrition and Health (INCIENSA), Cartago, Costa Rica.
Birth defects research
|August 2, 2024
概括
耳鼻裂 (OFC) 的患病率正在增加,特别是在综合征病例中,由于加强了监测. 这一趋势凸显了改善出生缺陷监测系统的重要性.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 出生缺陷 监视 监视 生产缺陷
背景情况:
- 耳脸裂 (OFC) 是一种常见的出生缺陷.
- 哥斯达黎加的出生缺陷登记中心 (CREC) 的改进始于2008年.
- 本研究分析了OFC从1996年到2021年的趋势.
研究的目的:
- 探索1996年至2021年间哥斯达黎加口腔裂 (OFC) 患病率的趋势.
- 分析2010年至2021年OFC的描述性数据.
- 评估监控系统改进对OFC报告的影响.
主要方法:
- 使用CREC数据对OFC (1996-2021) 的趋势分析和描述性分析 (2010-2021).
- 根据裂类型 (CP,CL±P) 和呈现 (孤立,非综合征,综合征) 的流行率计算.
- 趋势变化的关联点回归 (AAPC) 和流行率的Poisson回归.
主要成果:
- 对OFC的显著年平均百分比变化 (AAPC):整体+1.4%,非综合征+2.9%,综合征+7.7%.
- OFC的患病率从9.36/10,000 (1996-2009) 增加到11.86/10,000 (2010-2021),比率为1.3,这是一个很好的例子.
- 综合征性OFCs在两个时期之间显示了最高的患病率 (3.3).
结论:
- OFC的流行率呈现出日益增长的趋势.
- 国家出生缺陷监测系统的改进是这种观察到的增长的关键驱动力.
- 加强监测可以更准确地报告OFC,特别是综合征病例.
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