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电子血糖管理系统改善了血糖控制,减少了糖尿病患者接受冠状动脉旁路手术的并发症:一项随机对照试验
Alexandre Barbosa Câmara de Souza1, Marcos Tadashi Kakitani Toyoshima2, Priscilla Cukier1
1Department of Endocrinology and Metabolism, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Journal of diabetes science and technology
|August 3, 2024
概括
胰岛素APP电子血糖管理系统 (eGMS) 在冠状动脉旁路移植 (CABG) 手术后改善了2型糖尿病 (T2DM) 患者的血糖控制并减少了不良事件,提供了具有成本效益的解决方案.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 医疗信息学 医疗信息学
背景情况:
- 住院高血糖会增加糖尿病患者接受冠状动脉旁路移植 (CABG) 手术的风险.
- 电子血糖管理系统 (eGMS) 显示出改善医院环境中的血糖控制 (GC) 的潜力.
- 评估了InsulinAPP协议在优化GC和减少CABG后不良结果方面的有效性.
研究的目的:
- 评估InsulinAPP协议在治疗CABG后2型糖尿病 (T2DM) 患者高血糖症的有效性.
- 为了比较InsulinAPP协议对T2DM患者在CABG后的传统护理的结果.
- 确定InsulinAPP协议对不良事件,住院和成本的影响.
主要方法:
- 一项前性,随机的,开放的标签研究,涉及100名成年T2DM患者在CABG后.
- 患者被随机分为两组:常规护理 (gCONV) 和使用InsulinAPP (gAPP) 的eGMS协议.
- 主要结局是医院获得的感染,功能恶化和症状性心房律乱的组合;次要结局包括GC,低血糖,停留时间和费用.
主要成果:
- gAPP组的平均葡萄糖水平较低 (167.2比188.7毫克/分升,P=.040) 和葡萄糖>180毫克/分升的日数较少 (51.3%比74.8%,P=.011).
- 主要综合结局发生在16%的gAPP患者中,而CgONV中为58% (P<.010).
- 在gAPP中,低血糖的发病率较低 (4%对16%,P=.046),住院时间较短,成本较低.
结论:
- 在CABG手术后,InsulinAPP协议有效地优化了T2DM患者的血糖控制.
- 这种eGMS可以减少不良结果,包括感染,脏恶化和心律失常.
- 在这种患者群体中,InsulinAPP为住院糖尿病患者的治疗提供了一个具有成本效益的解决方案.
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