在急性冠状动脉综合征后,心脏时间间隔和发作性心力衰竭之间的关联
Caroline Løkke Bjerregaard1,2,3, Flemming Javier Olsen4,5,6, Kristoffer Grundtvig Skaarup4,5,6
1Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Hellerup, Denmark. bjerregaard.caroline@gmail.com.
缩短的缩射出时间 (ET) 和更高的心肌性能指数 (MPI) 与急性冠状动脉综合征 (ACS) 患者心力衰竭 (HF) 风险增加有关. 这些心脏时间间隔可以帮助预测ACS后的HF发展.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏衰竭研究研究
背景情况:
- 心脏时间间隔是心肌功能障碍和心力衰竭 (HF) 风险的关键指标.
- 急性冠状动脉综合征 (ACS) 患者特别容易患上HF.
研究的目的:
- 调查特定心脏时间间隔和ACS患者中HF发病率之间的关联.
- 为了识别回声心脏学标记,预测ACS后HF的发展.
主要方法:
- 研究了386名接受皮肤冠状动脉干预 (PCI) 的ACS患者.
- 进行心声扫描,包括组织多普勒扫描,以测量异体缩时间 (IVCT),异体缩时间 (IVCT),缩喷射时间 (ET) 和心肌性能指数 (MPI).
- 事件HF是主要结局,随访时间中位数为4.3年.
主要成果:
- 在随访期间,140名 (36%) 患者出现了事件性HF.
- 较高的MPI和较短的ET在多变量调整后显著与高频率风险增加有关.
- 在左心室喷射率 (LVEF) ≥36%的患者中,ET和HF之间的关联是显著的.
结论:
- 缩短的ET和升高的MPI是ACS患者发生HF的独立预测因素.
- 在ACS患者中,ET作为HF的有价值的预后标志物,特别是那些有保存或轻度受损的LVEF患者.
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