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Updated: Jun 18, 2025

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
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在肥胖和胰岛素耐药性中基因表达的代谢表观调节

Swapan K Das1, Mary E Comeau2, Carl D Langefeld2,3

  • 1Department of Internal Medicine, Section of Endocrinology and Metabolism, Medical Center Boulevard, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA. sdas@wakehealth.edu.

Metabolomics : Official journal of the Metabolomic Society
|August 3, 2024
PubMed
概括

代谢物影响脂肪组织中的DNA甲基化,影响与肥胖和胰岛素抵抗相关的基因. 这项研究揭示了非洲裔美国人的特定代谢物-CpG位点基因相互作用.

关键词:
这是Cis-eQTM.非洲裔美国人.通过DNA甲基化.胰岛素耐药性 胰岛素耐药性是一种代谢产物的代谢物肥胖问题 肥胖问题

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