长期COVID:临床更新
Trisha Greenhalgh1, Manoj Sivan2, Alice Perlowski3
1Nuffield Department of Primary Care Health Sciences, Radcliffe Observatory Quarter, Oxford, UK.
后COVID-19状态,或长期COVID,涉及影响多个器官的持续症状. 研究综合了目前有关其原因,影响和管理的知识,探索了新的个性化治疗途径.
科学领域:
- 关于COVID-19后 (长期COVID) 状况的多学科研究.
背景情况:
- 长期COVID被定义为急性COVID-19后持续3个月以上的症状.
- 它会造成严重的器官损伤,功能障碍和社会经济负担.
研究的目的:
- 综合长期COVID的流行病学,病理生理学,生活经验,临床方面和管理方面的文献.
- 探索基于机制的个性化护理的新方法.
主要方法:
- 综合多种研究流程的跨学科审查.
- 包括一个严重的长期COVID患者的生活经验.
主要成果:
- 长期的COVID会影响多个器官系统,并可能导致严重的,持久的损伤.
- 目前的护理在很大程度上是症状性的;表型和生物标志物的进步提供了未来的个性化策略.
结论:
- 对长期COVID的全面了解对于有效的管理至关重要.
- 未来的研究应侧重于基于机制的个性化干预和预防策略.
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