氨酸:关于合成,新陈代谢和营养的全面概述
Mudassar Hussain1, Imad Khan1, Muneeba Naseer Chaudhary2
1State Key Laboratory of Food Science and Resources, National Engineering Research Center for Functional Food, National Engineering Research Center of Cereal Fermentation and Food Biomanufacturing, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China.
酸丁素 (PtdS) 是一种阴性脂,对细胞信号传递和大脑功能至关重要. 虽然其在记忆中的作用尚不清楚,但PtdS是安全的,并且是一种潜在的功能性食品成分.
科学领域:
- 生物化学 生化学
- 神经科学是一个神经科学.
- 细胞生物学 细胞生物学
背景情况:
- 脂素 (PtdS) 是一种在神经组织中丰富的关键阳离子甘油脂.
- 它在细胞亡,血液凝固以及作为酸乙醇胺的前体中发挥着关键作用.
- 对于神经传递和神经炎症等中枢神经系统功能来说,PtdS是必不可少的.
研究的目的:
- 审查PtdS.的自然发生,生物合成和代谢.
- 讨论PtdS在中枢神经系统 (CNS) 中的作用.
- 探索食品中的PtdS强化及其对记忆力的潜在影响,并注意到目前的不确定性.
主要方法:
- 关于PtdS发生,生物合成 (酶,基因) 和新陈代谢的文献综述.
- 通过脂酶D (PLD) 检查PtdS酶合成.
- 对用于认知功能和安全的PtdS补充剂的研究分析.
主要成果:
- 通过PtdS合成酶-1和-2合成PtdS,并且可以通过PtdS脱碳酶生成PtdS.
- PtdS参与激活中枢神经系统中的信号通路,神经炎症,神经传输和突触精炼.
- 临床研究证实PtdS是安全和耐受的,尽管它对提高记忆力的有效性是不确定的.
结论:
- PtdS是一种多功能脂,具有关键的生物功能,特别是在大脑中.
- 它作为一种功能性食品成分的潜力,用于认知支持,需要进一步调查.
- PtdS是安全的消费,支持其在各种人口统计数据的强化食品中的使用.
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