在COVID-19大流行期间,荷兰的阿片类药物处方:基于国家注册的研究
Hannah Ellerbroek1,2, Arnt F A Schellekens3,2,4, Gerard A Kalkman5
1Department of Psychiatry, Radboud University Medical Center, Nijmegen, Netherlands hannah.ellerbroek@radboudumc.nl.
BMJ open
|August 3, 2024
概括
COVID-19大流行对荷兰的整体阿片类药物处方产生了有限的影响. 虽然新处方短暂下降,但慢性阿片类药物使用仍然是一个重大的公共卫生问题.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 药理学 药理学是指药理学的学科.
背景情况:
- COVID-19大流行扰乱了全球医疗保健,影响了阿片类药物处方模式.
- 在北美大流行期间,阿片类药物的销量下降,但与阿片类药物相关的死亡人数上升.
- 大流行病对欧洲阿片类药物处方的影响在很大程度上是未知的.
研究的目的:
- 在COVID-19大流行期间,描述荷兰的阿片类药物处方趋势.
- 分析封锁措施对阿片类药物处方率的影响.
- 评估不同患者人口统计数据中阿片类药物处方的变化.
主要方法:
- 一项基于登记的全国性研究,利用聚合的保险报销数据.
- 将大流行前两年的阿片类药物处方数据与大流行前的数据进行比较.
- 分析包括处方类型,患者的性别,年龄和社会经济地位,并探索锁定效应.
主要成果:
- 与大流行前水平相比,整体阿片类药物处方保持稳定.
- 在最初的封锁期间,观察到新的阿片类药物处方和年轻患者处方短暂下降.
- 基于性别,年龄和社会经济地位的阿片类药物获取现有的差异没有被大流行扩大.
结论:
- COVID-19大流行对荷兰的整体阿片类药物处方产生了有限的直接影响.
- 尽管总体数字稳定,但慢性阿片类药物使用仍然是一个关键的公共卫生问题,需要注意.
- 可能需要进一步的研究来了解长期的处方趋势及其影响.
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