甲状腺切除术后的甲状腺功能低下.甲状腺功能低下. 流行率和预测标记. 优甲状腺和高甲状腺结节性喉患者之间的比较
Luis García Pascual1, Carlos Puig-Jové1, Andreu Simó-Servat1
1Servei d'Endocrinologia, Hospital Universitari Mútua de Terrasa, Terrassa, Barcelona, Spain.
Endocrinologia, diabetes y nutricion
|August 3, 2024
概括
甲状腺切除术后的甲状腺功能低下症 (PHH) 在甲状腺切除术后很常见,甲状腺功能过高患者的患病率更高. 经典的标志物预测了平甲状腺患者的PHH,而体重超过70kg是甲状腺功能高患者的新型预测因素.
科学领域:
- 内分泌学 在内分泌学.
- 甲状腺手术 甲状腺手术
- 术后并发症 术后并发症
背景情况:
- 甲状腺瘤切除术后的甲状腺功能低下症 (PHH) 是一个常见的并发症 (22%-30%),我们地区的数据有限.
- 这项研究调查了PHH患病率和预测标记器在euthyroid对比甲状腺功能障碍患者接受甲状腺切除术.
研究的目的:
- 为了确定 posthemithyroidectomy 甲状腺功能低下症 (PHH) 的患病率.
- 识别和比较PHH的预测标记在患有先前存在的甲状腺症和甲状腺功能障碍的患者中.
主要方法:
- 追溯观察横截面研究.
- 包括106名患者:在甲状腺切除术之前88名甲状腺和18名甲状腺.
主要成果:
- 甲状腺炎患者中PHH患病率为42%,甲状腺炎患者中为50%.
- 优甲状腺患者的预测标记包括手术前的甲状腺激素≥2.2mIU/L,年龄≥50岁,剩余叶≤19.6%.
- 体重>70公斤成为甲状腺功能增高患者PHH的新型预测标志物.
结论:
- 这项研究报告的PHH发病率高于平均水平的乙甲状腺患者,在甲状腺功能障碍患者的发病率和强度增加.
- 鉴定了顺甲状腺患者的经典预测标记物和甲状腺功能高患者的新标记物 (体重>70公斤).
- 这些发现有助于评估PHH风险,并优化经过甲状腺切除术后的术后激素监测.
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