在被列为固体器官移植的患者中,COVID-19疫苗犹的原因
Sandhya Kalavacherla1, Nicole H Goldhaber2, Katherine Y Chen1
1School of Medicine, University of California San Diego, La Jolla, California.
Transplantation proceedings
|August 3, 2024
概括
列为固体器官移植 (LSOTP) 患者的患者由于安全性和必要性的担忧,对COVID-19疫苗表示犹. 需要有针对性的教育来解决这个高风险群体中的这些问题.
科学领域:
- 移植医学 移植医学
- 传染病流行病学 传染病流行病学
- 疫苗学 疫苗学 疫苗学
背景情况:
- 列为实体器官移植 (LSOTP) 的患者面临严重COVID-19的高风险.
- 尽管有建议,但在LSOTP.中仍然存在COVID-19疫苗的犹和使用不足.
- 这种犹的原因需要仔细研究.
研究的目的:
- 描述LSOTP中COVID-19疫苗犹的原因.
- 调查与移植清单相关的COVID-19疫苗的看法.
- 在这个群体中探索流感疫苗接种的经验.
主要方法:
- 单一中心的回顾性调查分析.
- 110个心脏,肝脏和脏LSOTP的电话调查.
- 对不完整的COVID-19疫苗接种和流感疫苗史的评估原因.
主要成果:
- 49.1%的患者做出了反应;常见的犹原因包括缺乏研究 (31%),害怕副作用 (22%),以及缺乏必要性 (20%).
- 35%的人在上市后改变了对疫苗的看法,他们经常认为COVID-19疫苗对移植接收者不安全 (32%).
- 54%的人始终接受年度流感疫苗;犹的性别差异在统计学上并不显著.
结论:
- 与安全性和必要性有关的LSOTP表现出显著的COVID-19疫苗犹.
- 结果可以指导有针对性的教育举措,以解决LSOTP中的误解.
- 在更大,多样化的队伍中进行进一步的研究对于理解和减轻疫苗犹是必不可少的.
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