认知刺激疗法对血管认知障碍患者认知的有效性:试点随机对照试验
Naoki Mori1,2,3, Yohei Otaka1,4, Daisuke Ito1,2
1Department of Rehabilitation Medicine, Tokyo Bay Rehabilitation Hospital, Chiba, Japan.
The Keio journal of medicine
|August 4, 2024
概括
在康复期间,认知刺激疗法 (CST) 在血管认知障碍患者中没有显著改善认知功能. 在两组中都观察到改善,这表明其他因素也可能起作用.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 认知科学 认知科学
背景情况:
- 血管认知障碍 (VCI) 影响认知功能.
- 认知刺激疗法 (CST) 在VCI康复中的作用尚未得到充分研究.
- 没有先前的研究研究了VCI康复期康复期的CST.
研究的目的:
- 检查CST对VCI患者认知功能的影响.
- 评估CST在康复者康复环境中的有效性.
- 为了比较CST和传统康复治疗之间的认知结果.
主要方法:
- 一个随机对照的,评估者盲目的,单中心的试验.
- 20名患有VCI的参与者被分配到CST或对照组8周.
- 认知功能使用微型心理状态检查 (MMSE) 进行测量,并使用通用线性混合模型 (GLMM) 进行分析.
主要成果:
- 从基线到第8周,CST和对照组的MMSE得分均显著改善.
- 在CST和对照组之间没有发现MMSE得分的显著差异.
- GLMM表明时间对MMSE得分有显著的影响,但不是群体或时间群体的相互作用.
结论:
- 在VCI患者的认知功能方面,CST没有显示出与传统康复相比的显著额外益处.
- 观察到的改善可能归因于恢复的自然过程或常规康复.
- 需要进行更大的样本大小研究来证实这些发现,并探索潜在的掩盖效应.
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