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胰腺管切除术后的临床病理学评估 内血管治疗的出血与内血管治疗
Tomoko Kugiyama1, Masamichi Koganemaru1, Akiko Sumi1
1Department of Radiology, Kurume University School of Medicine.
The Kurume medical journal
|August 4, 2024
概括
血管内治疗对胰腺切除术后出血 (PPH) 有希望. 胰腺脂肪透没有影响结果,但出血性休克和出血倾向与死亡率和并发症有关.
科学领域:
- 胃肠病学 胃肠病学
- 干预性放射学 干预性放射学
- 手术并发症 手术并发症
背景情况:
- 胰腺切除术后出血 (PPH) 是胰腺手术后的一种严重并发症.
- 胰腺脂肪透或纤维化是胰腺的已知危险因素.
- 胰腺组织的组织病理学评估可以提供预后见解.
研究的目的:
- 评估PPH患者的干预程序的预后因素.
- 调查胰腺脂肪透/纤维化与PPH内血管治疗后的结果之间的关联.
- 评估PPH内血管治疗的有效性和安全性.
主要方法:
- 对接受内血管治疗的29名PPH患者的回顾性分析 (2001年9月 - 2020年3月).
- 单变量分析以确定胰腺组织病理特征,并发症和死亡率之间的关联.
- 评估内血管干预的技术和临床成功率.
主要成果:
- 内血管治疗的高技术 (97%) 和临床 (87%) 成功率.
- 住院死亡率为17% (5/29名患者).
- 没有发现胰腺囊与组织病理性脂肪透/纤维化之间存在关联.
- 出血性休克前治疗与住院死亡率有显著的相关性 (P=0.017).
- 出血倾向与治疗后并发症相关 (P=0.033).
结论:
- 内血管治疗似乎有效地管理PPH.
- 胰腺脂肪透/纤维化组织病理程度没有显著影响临床成功或预后.
- 出血性休克和出血倾向是影响PPH患者接受内血管治疗的临床结果的关键因素.
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