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在CAR-T细胞疗法中抗原逃逸:机制和克服策略

Haolong Lin1, Xiuxiu Yang1, Shanwei Ye1

  • 1Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China; Immunotherapy Research Center for Hematologic Diseases of Hubei Province, Wuhan, Hubei 430030, China.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|August 4, 2024
PubMed
概括

卡特-T细胞疗法显示有前途,但面临抗原逃逸,导致复发. 本综述详细介绍了逃避机制和策略,以提高CAR-T疗法的有效性,以获得更好的癌症治疗结果.

关键词:
抗原逃逸的方法化学抗原受体T细胞治疗瘤复发的情况克服战略 克服战略

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