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Updated: Jun 18, 2025

Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides
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Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides

Published on: July 26, 2018

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为了高效的聚达丁合成,可利用甘氨基转移酶的工程区域选择性

Fucheng Zhu1, Jingli Dai2, Zixu Yan2

  • 1College of Biological and Pharmaceutical Engineering, Anhui Engineering Laboratory for Conservation and Sustainable Utilization of Traditional Chinese Medicine Resources, Anhui Province Key Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, West Anhui University, Lu'an city 237012, China.

Food chemistry
|August 4, 2024
PubMed
概括

分子进化增强了一种Bacillus subtilis尿素二酸盐依赖的葡萄糖转移酶 (UGT),以改善复醇的糖化. 一个三重突变通过增强的酶基质相互作用有效地产生了功能性食品成分聚达丁.

关键词:
料批量级联反应反应的级联反应分子进化的分子进化.导航方向 导航方向 导航方向区域活动性 区域活动性

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相关概念视频

Oligosaccharide Assembly01:24

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...
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