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相关概念视频

Liver Physiology01:30

Liver Physiology

464
The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of  70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
464
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

496
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
496
Liver Regeneration01:24

Liver Regeneration

3.2K
The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
3.2K
Liver Histology01:27

Liver Histology

661
The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
661

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相关实验视频

Updated: Jun 18, 2025

Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen
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Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen

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急性肝功能衰竭

Rakhi Maiwall1, Anand V Kulkarni2, Juan Pablo Arab3

  • 1Department of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India.

Lancet (London, England)
|August 4, 2024
PubMed
概括

急性肝衰竭 (ALF) 是一种严重的疾病,需要及时诊断和治疗. 了解病因多样性和早期干预对于改善患者的治疗结果和生存率至关重要.

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Heterotopic Auxiliary Rat Liver Transplantation With Flow-regulated Portal Vein Arterialization in Acute Hepatic Failure
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相关实验视频

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Heterotopic Auxiliary Rat Liver Transplantation With Flow-regulated Portal Vein Arterialization in Acute Hepatic Failure
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科学领域:

  • 肝病学
  • 危急护理医学

背景情况:

  • 急性肝衰竭 (ALF) 是肝功能快速下降而没有先前存在的肝病.
  • 它具有凝血病和肝脏脑病,具有显著的死亡风险.

研究的目的:

  • 在全球范围内审查ALF的各种原因.
  • 讨论ALF的预后模型和当前的管理策略.
  • 强调早期发现和干预的重要性.

主要方法:

  • 对ALF的病因,预后和治疗进行了全面的文献审查.
  • 分析常见的病因因素,包括药物毒性,病毒感染和自身免疫性疾病.
  • 评估治疗方案,包括支持性护理,肝移植和人工肝支持系统.

主要成果:

  • ALF的原因在地理上有所不同,常见的是药物毒性和病毒感染.
  • 败血症和脑是ALF患者死亡的主要原因.
  • 肝移植是最好的治疗方案,

结论:

  • 及时的病因调查对于指导ALF的治疗和预后至关重要.
  • 早期识别和适当的治疗,包括潜在的移植,可以显著改变ALF的结果.
  • 多学科治疗对于治疗败血症和脑等并发症至关重要.