两步或一步 - - 所有新生儿化器消毒方法都是一样的吗?
1Department of Civil, Environmental and Geomatic Engineering, University College London, London, UK.
The Journal of hospital infection
|August 4, 2024
概括
两步消毒有效地从新生儿化器表面去除了微生物标记物,与单步擦拭不同. 然而,在床上仍然存在标记物,这凸显了新生儿重症监护室 (NICU) 需要改进的净化策略的需要.
科学领域:
- 预防和控制感染的预防和控制.
- 微生物学 微生物学
- 生物医学工程 生物医学工程
背景情况:
- 与医疗保健相关的病原体在新生儿重症监护室 (NICU) 中构成风险.
- 有效的化器清除污染对于感染控制至关重要.
- 建议进行潜水消毒,但并不总是可行的,导致使用擦拭消毒.
研究的目的:
- 为了比较两步 (酶洗剂浸泡 + 低化物擦拭) 与一步 (四级化合物擦拭) 脱污程序的有效性.
- 评估从新生儿化器表面去除微生物替代标记物的情况.
- 在终端清除污染后,确定化器组件上的潜在微生物持久性.
主要方法:
- 在化器表面 (风扇,床,门) 接种了三种源自花马赛克病毒的微生物替代标记物.
- 应用了两种除污方法:一阶段 (四级化合物抹布) 和两阶段 (酶性洗剂浸泡,然后用低化物抹布).
- 使用定量PCR (qPCR) 检测了28个污染点的标记物存在.
主要成果:
- 两步消毒导致11%的遗址呈阳性,而一步消毒则导致43%的遗址呈微生物标记的阳性.
- 微生物标记物在单步消毒过程中转移到其他表面,特别是从门上.
- 在化器床上接种的标记物在一阶段和两阶段的消毒程序后仍然存在.
结论:
- 单一的消毒不够从新生儿化器表面完全去除微生物标记物.
- 两步消毒更有效,特别是在潜水组件,但不是床.
- 在化器表面,特别是床上的微生物持久性,强调了优化新生儿重症监护室终端消毒协议的重要性.
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