自闭症谱系障碍与儿童肠道微生物群之间的复杂相互作用:综合性综述
Rongrong Yu1, Rahila Hafeez2, Muhammad Ibrahim2
1College of Education, Zhejiang University of Technology, Hangzhou 310023, China.
Behavioural brain research
|August 4, 2024
概括
本综述探讨了肠道微生物群与儿童自闭症谱系障碍 (ASD) 之间的联系. 它检查了肠道细菌的变化,潜在的机制,以及对ASD症状的益生菌等治疗方法.
科学领域:
- 神经科学是一个神经科学.
- 微生物学 微生物学
- 发育儿科 发育儿科
背景情况:
- 自闭症谱系障碍 (ASD) 涉及社交沟通缺陷和重复性行为.
- 患有自闭症儿童经常出现胃肠道 (GI) 问题,高达80%的儿童受到影响.
- 肠道微生物群在肠道健康和功能中起着至关重要的作用.
研究的目的:
- 审查肠道微生物群与儿童的自闭症之间的潜在联系.
- 讨论有关ASD儿童肠道细菌组成的最新发现.
- 探索肠-大脑轴影响机制和潜在的治疗策略.
主要方法:
- 关于肠道微生物群和ASD的最新数据的文献综述.
- 对调查肠道细菌组成变化的研究进行分析.
- 检查将肠道微生物群与ASD症状联系在一起的拟议机制.
主要成果:
- 患有自闭症的儿童表现出改变的肠道微生物群组成.
- 肠道微生物群可能会影响大脑功能,并通过肠-大脑轴促进ASD症状.
- 饮食干预,益生菌和后生菌是潜在的治疗途径.
结论:
- 肠道微生物群和自闭症之间存在复杂的关系,需要进一步研究.
- 了解肠-大脑轴对于阐明ASD机制至关重要.
- 需要标准化研究方法来确认因果关系并开发有效的治疗方法.
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