尼古丁的吸入和新陈代谢会触发AOX介导的超氧化物生成,并导致氧化性肺损伤

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Jay L Zweier1, Tapan Kundu1, Mahmoud S Eid1

  • 1Division of Cardiovascular Medicine, and the EPR Center, Department of Internal Medicine, Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, Columbus, Ohio, USA.

The Journal of biological chemistry
|August 4, 2024
PubMed
概括

电子烟中的高尼古丁含量 (NIC) 可以导致肺损伤. 尼克代谢触发超氧化物生成通过阿尔代氧化酶 (AOX),导致氧化性肺损伤,特别是在慢性vaping.

关键词:
在EPR旋转陷中使用EPR.阿尔德海德氧化酶的使用.电子烟是一种电子烟.自由基是自由基的重要组成部分.超氧化物超氧化物

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