心血管磁共振特征跟踪衍生应变分析可以预测在运动热中风后恢复训练
1Department of Radiology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210002 Jiangsu, China.
概括
通过心血管磁共振 (CMR) 测量的二维全球纵向应变 (GLS) 可以预测经历过运动热中风 (EHS) 的士兵的恢复训练 (RTT). 损伤的2D-GLS是军事人员康复的关键预后标志物.
科学领域:
- 心血管成像和诊断系统
- 体育医学和军事健康 运动医学和军事健康
- 生物标志物的发现和预测.
背景情况:
- 劳动热中风 (EHS) 在年轻,训练有素的士兵中越来越令人担忧,但缺乏可靠的恢复预后标志物.
- 了解影响恢复训练 (RTT) 的因素对于军事准备和士兵在EHS之后的福祉至关重要.
- 心血管磁共振 (CMR) 提供先进的成像能力,以非侵入性评估心脏功能.
研究的目的:
- 评估从CMR特征追踪获得的左心室 (LV) 菌株参数的实用性,以作为患有EHS的士兵中RTT的预后生物标志物.
- 确定特定的CMR衍生LV菌株指标,可以预测EHS后成功恢复训练.
- 将LV菌株参数的预测性能与临床模型和传统CMR参数进行比较.
主要方法:
- 预期包括接受CMR电影序列的被诊断患有EHS的训练有素士兵.
- 导出二维 (2D) LV菌株参数,专注于全球纵向菌株 (GLS).
- 在CMR后3个月评估RTT,定义为没有持续的心脏症状和反复的热病;多变量逻辑回归和AUC分析用于模型比较.
主要成果:
- 分析了80名患有EHS和27名健康对照的士兵;32名EHS参与者在3个月内没有达到RTT.
- 与对照组相比,EHS参与者的二维全球纵向菌株 (2D-GLS) 显著受损,并且在RTT和非RTT组之间存在差异.
- 2D-GLS ≤-15.0%的值成为RTT的独立预测指标,提供了超出临床和传统CMR模型的增量预后价值 (AUC 0.88与0.72/0.79).
结论:
- 来自CMR的二维全球纵向菌株 (2D-GLS) 是一个有价值的预后生物标志物,用于预测从运动热中风中恢复过来的士兵恢复训练.
- 2D-GLS ≤-15.0%的特定切线显示出显著的预测能力,有助于军事人员的临床决策.
- 对LV菌株的CMR特征追踪提供了对管理EHS恢复和确保士兵健康至关重要的增强预后信息.
相关概念视频
Exercise Stress Test
186
Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
186
Exercise and Cardiovascular Response
760
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
760


