转移到脑膜瘤的转移情况的综述,并提供案例
Magnus Sættem1,2, Terje Sundstrøm1,3, Anna K Myrmel Sæle3,4
1Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway.
Brain & spine
|August 5, 2024
概括
瘤到瘤转移 (TTM) 是罕见的,乳腺癌是瘤到脑膜瘤转移 (TMM) 的更常见原因,而不是前列腺癌. 对TMM的认识对于癌症患者的管理和监测至关重要.
科学领域:
- 在瘤学瘤学.
- 神经病理学神经病理学
背景情况:
- 瘤到瘤转移 (TTM) 描述了一种罕见的转移性事件,主要恶性瘤扩散到另一个瘤.
- 脑膜瘤,通常是良性脑瘤,是TTM中最常见的受体瘤.
- 由于癌症和脑膜瘤的患病率日益增加,瘤转移到脑膜瘤转移 (TMM) 需要仔细考虑.
研究的目的:
- 介绍两个涉及前列腺癌和乳腺癌的TMM病例.
- 审查关于TTM的文献,重点关注TMM及其生物机制.
- 突出TMM在手术和瘤治疗策略中的临床影响.
主要方法:
- 对两个患有TMM的患者的电子病历进行了回顾性审查.
- 对TTM和TMM案例进行全面的文献搜索.
- 对TMM背后的生物机制的分析.
主要成果:
- 确定了两个TMM病例:一个来自前列腺癌,一个来自乳腺癌.
- 乳腺癌是TMM比前列腺癌更常见的原因 (50个审查的病例与15个描述的前列腺癌病例).
- 一名患者患有WHOI级脑膜瘤与前列腺癌引起的TMM;另一个患有WHOII级脑膜瘤与乳腺癌引起的TMM.
结论:
- 瘤转移为脑膜瘤的转移是一个不常见但具有临床意义的事件.
- 主要瘤的起源会影响TMM的发生频率,乳腺癌比前列腺癌更常见.
- 承认TMM对于适当的患者管理至关重要,包括手术规划,瘤治疗和监测协议.
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