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Updated: Jun 18, 2025

Single-Molecule Imaging of EWS-FLI1 Condensates Assembling on DNA
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通过先驱转录因子解染色体的结构动力学

Andrea Orsetti1, Daphne van Oosten1, Roxana-Geanina Vasarhelyi2

  • 1Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, Netherlands.

Biophysical reviews
|August 5, 2024
PubMed
概括

先驱转录因子调节基因活动和染色质结构. 这篇评论探讨了这些因素如何打开色素,并建议将NMR光谱与分子动力学模拟相结合,以研究这些动态过程.

关键词:
染色是一种染色素.开拓者转录因子的先驱.结构动力学 结构动力学

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Transcription Elongation Factors

Transcription elongation is a dynamic process that alters depending upon the sequence heterogeneity of the DNA being transcribed. Hence, it is not surprising that the elongation complex's composition also varies along the way while transcribing a gene.
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