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生命至关重要 8 关于糖尿病患者心血管疾病和死亡率的关系
Wenjuan Li1,2, Aijun Xing2, Wenqi Xu1
1School of Clinical Medicine, North China University of Science and Technology, Tangshan, Hebei, China.
JACC. Asia
|August 5, 2024
概括
改善生活必需品8 (LE8) 评分,衡量心血管健康,显著降低心血管疾病 (CVD) 风险和2型糖尿病 (T2D) 患者的死亡率. 维持或增加LE8对于改善该人口的健康结果至关重要.
科学领域:
- 心血管健康 心血管健康
- 糖尿病管理 糖尿病管理
- 公共卫生 公共卫生
背景情况:
- 关于生活必需品8 (LE8) 评分对2型糖尿病 (T2D) 患者的健康影响的证据有限.
- 了解这些关联对于开发针对T2D人口的有针对性的健康干预措施至关重要.
研究的目的:
- 研究LE8得分与T2D患者心血管疾病 (CVD) 和死亡风险之间的关系.
- 评估LE8得分随时间变化对T2D患者健康结果的影响.
主要方法:
- 一项针对19,915名患有T2D的中国参与者的前性队列研究 (Kailuan研究,2006-2020).
- 根据饮食,体育活动,吸烟,睡眠,BMI,血脂,血糖和血压,每两年评估一次LE8得分.
- 时间变化的Cox模型用于分析LE8得分与心血管疾病发病率/死亡率之间的关联.
主要成果:
- 较高的LE8得分与较低的心血管疾病发病率和总死亡率风险显著相关.
- 与最低五分位数相比,最高的LE8五分位数显示风险降低:心血管疾病为44%,心脏病为47%,中风为47%,总死亡率为27%.
- 在糖尿病诊断后增加LE8分数进一步降低了心血管疾病和死亡率的风险,降低了17%-42%.
结论:
- 较高的LE8得分与T2D成年人心血管疾病和死亡风险明显降低有关.
- 通过LE8组件改善心血管健康可以减轻2型糖尿病患者的严重健康风险.
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