语音处理低于预期,并且与多发性硬化症患者的词查找困难有关
Emily Dvorak1,2, Sarah Levy1, Jordyn R Anderson1
1Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Multiple sclerosis (Houndmills, Basingstoke, England)
|August 5, 2024
概括
音声处理缺陷在复发性复发性多发性硬化症 (RRMS) 中很常见,并且与查词困难直接相关. 这表明早期的大脑变化可能会影响RRMS患者的言语.
科学领域:
- 神经学 神经学
- 语音语言病理学 语言病理学
- 认知神经科学 认知神经科学
背景情况:
- 难以找到单词是复发性复发性多发性硬化症 (RRMS) 患者常见但不太了解的症状.
- 了解词找困难的潜在机制对于开发有效的干预措施至关重要.
研究的目的:
- 调查RRMS患者声学处理能力受损的假设.
- 在这个人群中确定语音处理缺陷和词查找困难之间的关系.
主要方法:
- 五十名RRMS患者被评估为患者报告的词查找困难 (PR-WFD).
- 目标表现使用韦克斯勒个人成就测试,第四版 (WIAT-4) 测量,包括语音熟练程度 (PP),文字阅读 (WR) 和句子重复 (SR).
主要成果:
- 在RRMS患者中,Phonemic Proficiency (PP) 评分明显低于规范期望.
- 患者报告的更糟糕的词查找困难 (PR-WFD) 特别与较低的语音能力 (PP) 绩效有关.
- 单词阅读 (WR) 和句子重复 (SR) 的表现与规范期望没有显著差异,与PR-WFD无关.
结论:
- 语音处理在RRMS患者中明显低于预期,并且与难以找到单词有关.
- 这些发现支持了早期疾病相关的皮质变化影响RRMS声学处理的假设.
- 这些结果有助于在多发性硬化症中发现单词困难的不断变化的模型.
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