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Updated: Jul 14, 2026

The ChroP Approach Combines ChIP and Mass Spectrometry to Dissect Locus-specific Proteomic Landscapes of Chromatin
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阶段分离:一种基于阶段分离的基因编码报告器,用于活细胞中H3K9三甲基化

Renxi He1, Tian Dong1, Jingyi Chu2

  • 1National Biomedical Imaging Center, College of Future Technology, State Key Laboratory of Membrane Biology, School of Life Sciences, and Biomedical Pioneering Innovation Center (BIOPIC), Peking University, Beijing, 100871, China.

Analytical chemistry
|August 5, 2024
PubMed
概括

研究人员开发了一种新的生物传感器Phaser-Trim,用于跟踪活细胞中组织素甲基化 (H3K9me3) 动态. 这种工具为疾病研究和药物发现提供了更好的灵敏度和特异性.

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相关概念视频

Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
Commonly used reporter...