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Updated: Jun 18, 2025

Roux-en-Y Gastric Bypass Operation in Rats
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重新定义斯坦丁剂量 胃外置术后:来自人口药理动力学-药理动力学链接方法的见解

Ana Carolina Conchon Costa1, Jose Ivan Marques Medeiros2, Wonho Kang1

  • 1Center for Pharmacometrics and Systems Pharmacology, College of Pharmacy, University of Florida, Orlando, Florida, USA.

Journal of clinical pharmacology
|August 5, 2024
PubMed
概括

鲁克斯-en-Y胃绕道 (RYGB) 显著减少了对simvastatin乳 (SV) 和其活性代谢物 (SVA) 的暴露40%. 后RYGB患者可能需要更高的simvastatin剂量或非他类药物,以获得类似的降胆固醇效果.

关键词:
在OATP1B1基因型中.PopPK PopPK 这是一个很大的问题.胃绕道术是指胃绕道术.西姆瓦斯塔丁氧化酸是什么

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