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相关概念视频

Phylogenetic Trees03:21

Phylogenetic Trees

45.3K
Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.
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Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.7K
Phylogeny01:23

Phylogeny

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Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.
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Survival Tree01:19

Survival Tree

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Survival trees are a non-parametric method used in survival analysis to model the relationship between a set of covariates and the time until an event of interest occurs, often referred to as the "time-to-event" or "survival time." This method is particularly useful when dealing with censored data, where the event has not occurred for some individuals by the end of the study period, or when the exact time of the event is unknown.
 Building a Survival Tree
Constructing a...
74
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

7.1K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
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Per-Unit Sequence Models01:26

Per-Unit Sequence Models

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An ideal Y-Y transformer, grounded through neutral impedances, displays per-unit sequence networks akin to those of a single-phase ideal transformer when subjected to balanced positive- or negative-sequence currents. These currents do not produce neutral currents, and their associated voltage drops.
Zero-sequence currents, which are identical in magnitude and phase, generate a neutral current, resulting in voltage drops across the neutral impedance and the low-voltage winding. If the...
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相关实验视频

Updated: Jun 18, 2025

A Practical Guide to Phylogenetics for Nonexperts
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A Practical Guide to Phylogenetics for Nonexperts

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贝叶斯系遗传学变异超级树的变异超级树

Michael D Karcher1,2, Cheng Zhang3, Frederic A Matsen4

  • 1Department of Math & CS, Muhlenberg College, 2400 W Chew St, Allentown, PA, 18104, USA. michaelkarcher@muhlenberg.edu.

Bulletin of mathematical biology
|August 5, 2024
PubMed
概括
此摘要是机器生成的。

这项研究引入了一种变异性方法,将重叠的数据集中的家族遗传树结合起来. 它提供了一种计算效率高的方法,可以在不需要重新运行昂贵的分析的情况下,对组合的遗传学结果进行近似计算.

关键词:
分裂并征服 - 分裂并征服梯度下降是一种梯度下降.人类遗传学 是一个学科.这就是超级树的超级树.变量方法 变量方法

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Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
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Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

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Amplification of Near Full-length HIV-1 Proviruses for Next-Generation Sequencing
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Amplification of Near Full-length HIV-1 Proviruses for Next-Generation Sequencing

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相关实验视频

Last Updated: Jun 18, 2025

A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

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Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

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Amplification of Near Full-length HIV-1 Proviruses for Next-Generation Sequencing
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Amplification of Near Full-length HIV-1 Proviruses for Next-Generation Sequencing

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科学领域:

  • 计算生物学 计算生物学
  • 人类遗传学 是一个学科.
  • 统计推理 统计推理

背景情况:

  • 贝叶斯的基因推理是计算密集的.
  • 从重叠的数据集中结合遗传学结果通常需要重新运行昂贵的分析.
  • 现有的方法缺乏有效的方法来近似组合的遗传学后期.

研究的目的:

  • 开发一种计算效率高的方法,通过重叠的数据集来近似结合后遗传分布.
  • 提供一种利用现有的遗传学分析而无需重新计算的方法.
  • 为了应对将分类群的子集的遗传学结果结合起来所面临的挑战.

主要方法:

  • 开发了一种变异性方法,以近似结合后遗传学后遗传.
  • 创建了一个算法来确定整个分类群的变化分布的支持.
  • 梯度下降算法用于最大限度地减少子集分布和组合分布之间的分歧.

主要成果:

  • 拟议的变异性方法有效地接近了组合的遗传学后部分布.
  • 该方法表明,与对组合数据集的重复运行分析相比,可以节省计算成本.
  • 这些算法成功地优化了对整个分类群的基因树拓学的概率分布.

结论:

  • 变异性方法为从重叠的数据中结合家族遗传树提供了显著的计算优势.
  • 这种方法使研究人员能够高效地近似结合的遗传学结果,节省计算资源.
  • 开发的算法为从分区的数据集中推断族系提供了实际的解决方案.