在男性麻风患者中出现的阴性腺和相关因素
Nafyad Tolossa Urgie1, Miftah Oumer Surur2, Shimelis Nigussie2
1Department of Biomedical Sciences, College of Health Sciences, Arsi University, Asela, Ethiopia.
PLoS neglected tropical diseases
|August 5, 2024
概括
麻风病通常会导致男性的阴性腺体缺陷,影响超过四分之一的患者. 超重和严重残疾是这种荷尔蒙失衡的关键风险因素.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 疯病是一种慢性传染病,会影响多个器官,包括丸.
- 在麻风症中,丸功能障碍经常导致阴性腺功能低下,其特点是丸激素水平较低.
- 麻风患者的阴性腺症往往未被诊断和报告,这突显了患者护理中的关键差距.
研究的目的:
- 为了确定男性麻风病患者中阴性性恋的患病率.
- 在这个人群中识别与阴性腺体缺陷症相关的因素.
- 为了研究低阴性和麻风患者的临床特征之间的关系.
主要方法:
- 一项涉及146名年龄在18-65岁之间的男性麻风患者的横截面研究.
- 通过患者病历审查和采访收集数据,包括老年男性雄激素缺乏症问卷.
- 使用电化学发光测量血清总,化激素 (LH) 和卵泡刺激激素 (FSH) 水平;统计分析包括斯皮尔曼相关性和多变量逻辑回归.
主要成果:
- 低阴性恋的患病率为26.7% (146名患者中有39名),主要的低阴性恋患者为87.2%,次要的低阴性恋患者为12.8%.
- 总丸激素与身体质量指数 (BMI),LH和FSH有反向相关性,但与年龄无关.
- 超重 (BMI) 和II级残疾被确定为催眠症的独立风险因素 (AOR=1.32和AOR=3.80).
结论:
- 在男性麻风患者中,很大一部分 (近四分之一) 患有阴性腺体缺陷症.
- 超重和II级残疾独立地与麻风病患者患子症的风险增加有关.
- 这些发现强调了查患有大麻病的病人,特别是那些超重或有严重残疾的人的阴性腺体查的重要性.
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