饮用水中的和膀癌:密歇根州的一项病例对照研究
Perpetua Uduba1, Lissa Soares2, Tesleem Babalola2
1Department of Biology Stony Brook University.
Health physics
|August 5, 2024
概括
这项研究没有发现饮用水或脚中的增加了膀癌的风险. 对饮用水源的进一步调整没有改变研究结果,这表明没有显著的关联.
科学领域:
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
- 流行病学 流行病学
背景情况:
- 在地下水中自然存在,可能带来放射性和化学健康风险.
- 摄入的可以导致毒性,影响膀和脏等器官.
- 饮用水中天然存在的度所带来的健康风险尚未完全被理解.
研究的目的:
- 研究饮用水中的含量与膀癌风险之间的联系.
- 通过基于人口的病例控制研究设计来评估这种关系.
- 在分析中探索潜在的混因素和选择偏差.
主要方法:
- 在密歇根州东南部进行了一项病例控制研究,其中包括411例膀癌病例和566例对照病例.
- 在参与者的饮用水和指甲样本中测量了度.
- 使用无条件后勤回归模型来评估暴露与膀癌症风险之间的关联,并根据生活方式和住院病史进行调整.
主要成果:
- 饮用水中的中位度为0.12μg/L,脚指甲中的中位度为0.0031μg/g.
- 最初的调整模型表明,饮用水和脚指甲中较高的四分位数具有潜在的保护作用.
- 对饮用水源的进一步调整减轻了这些发现,没有显示增加的风险 (水的HR为0.68,脚指甲的HR为0.80).
结论:
- 这项病例控制研究没有发现与饮用水或脚指甲中的暴露相关的膀癌风险增加的证据.
- 该研究强调了考虑饮用水源的重要性,以解决环境暴露研究中的潜在偏见.
- 研究结果表明,在研究范围内的饮用水中天然存在的含量不会增加膀癌风险.
更多相关视频
11:02Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
21.2K
09:51Methods for Analyzing the Impacts of Natural Uranium on In Vitro Osteoclastogenesis
Published on: January 30, 2018
8.1K
相关概念视频
02:59Cancer Prevention
6.1K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.1K
01:20Disorders of the Urinary System
271
The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
271