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在癌症中改变心理状态
John Y Rhee1,2,3, Vihang Nakhate1,3,4, Christy Soares5
1Division of Neuro-Oncology, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts.
Seminars in neurology
|August 5, 2024
概括
癌症患者的精神状态变化 (AMS) 有很多原因,包括癌症的扩散和治疗副作用. 本综述概述了AMS的临床方法和癌症特异性原因.
科学领域:
- 在瘤学瘤学.
- 神经学 神经学
- 内部医学 内部医学
背景情况:
- 癌症患者经常表现出改变的精神状态 (AMS).
- 多种因素导致癌症中的AMS,包括直接的中枢神经系统入侵,乳腺膜扩散和瘤相关的并发症.
- 癌症治疗及其后果,如神经毒性,感染和代谢障碍,也可以导致AMS.
研究的目的:
- 描述一种临床方法来评估患有AMS的癌症患者.
- 讨论AMS在癌症患者群体中的各种病因.
- 为突出AMS的癌症特异性差异诊断.
主要方法:
- 文献综述侧重于癌症患者的精神状态变化.
- 讨论AMS的常见和癌症特异性原因.
- 对诊断和管理的临床框架的介绍.
主要成果:
- 癌症患者的AMS源于直接的瘤影响,治疗毒性和全身并发症.
- 毒代谢性脑病变和妄想等常见原因是相关的,但癌症特异性因素需要特别考虑.
- 系统的方法对于确定AMS的根本原因至关重要.
结论:
- 癌症患者的精神状态改变是一个复杂的问题,具有多因素的起源.
- 综合差异诊断,包括癌症特异性病因,对于有效的管理至关重要.
- 临床评估应将一般的神经学原则与癌症特异性考虑相结合.
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