在幻觉感知中大脑的子测试:神经病痛和耳的多感官一致性
Dirk De Ridder1, Divya Adhia1, Sven Vanneste2
1Unit of Neurosurgery, Department of Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Brain research
|August 5, 2024
概括
慢性疼痛和耳声可能是充满记忆的幻觉感知. 大脑连接研究显示,感官皮层与副海马体进行通信,这表明多感官治疗可以帮助管理这些疾病.
科学领域:
- 神经科学是一个神经科学.
- 感官处理 感官处理
- 疼痛和耳研究的研究.
背景情况:
- 慢性神经病痛和耳通常被描述为幻觉感知.
- 感官脱差可以导致大脑使用记忆来填补缺少的感官信息.
研究的目的:
- 调查慢性疼痛和耳患者的大脑活动和功能连接.
- 探索感官皮层和副海马体在幻觉感知中的作用.
主要方法:
- 休息状态电脑图 (EEG) 对150名参与者进行了 (50名有耳,50名有慢性疼痛,50名健康对照).
- 来源局部化的电流密度从感觉皮层和近海马区域记录下来.
- 通过在各种频段 (gamma,theta) 中使用滞后相同步来评估功能连接.
主要成果:
- 与预测错误相关的马波段活动在疼痛和耳组的感觉皮层 (不包括嗅觉/口味) 中观察到.
- 在大多数感官皮层和副海马体之间发现了泰达频率连接,但在单个感官皮层之间没有.
- 这表明一种模型,感官剥夺导致准海马体使用存储的多感官信息来填补感知差距.
结论:
- 疼痛和耳涉及异常的玛和太频段活动和改变的功能连接模式.
- 一个新的概念表明,准海马体使用多感官一致性来填充不同的感官信息.
- 这种理解可能会导致治疗慢性疼痛和耳的新型多感官或副海马向治疗方法.
相关概念视频
Nociception
27.8K
Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
27.8K
Synesthesia
116
Synesthesia is a remarkable condition where stimulation of one sensory or cognitive pathway leads to automatic, involuntary experiences in a second sensory or cognitive pathway. People with synesthesia experience a blending or crossing of their senses, such as sight and sound, leading to cross-modal sensations. In this condition, the stimulation of one sense, such as hearing a number or musical note, triggers an experience of another sense, like sensing a specific color, taste, or smell. People...
116
Introduction to Special Senses
5.7K
Sensory receptors play an integral part in comprehending our external and internal environments. They receive diverse stimuli, converting them into the nervous system's electrochemical signals. This conversion occurs as the stimulus alters the sensory neuron's cell membrane potential, instigating the generation of an action potential. This action potential is subsequently transmitted to the central nervous system (CNS), which integrates with other sensory data or higher cognitive...
5.7K
Somatosensation
36.5K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
36.5K


